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    DNA/RNA Shield Collection Tube w/ Swab


    Cat # Name Size Price Quantity
    R1106 DNA/RNA Shield Collection Tube w/Swab (1 ml fill - RUO) 10 pack $72.10
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    R1107 DNA/RNA Shield Collection Tube w/Swab (1 ml fill - RUO) 50 pack $334.80
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    R1108 DNA/RNA Shield Collection Tube w/Swab (2 ml fill - RUO) 10 pack $77.30
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    R1109 DNA/RNA Shield Collection Tube w/Swab (2 ml fill - RUO) 50 pack $360.50
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    R1107-E DNA/RNA Shield Collection Tube w/Swab (1 ml fill - CE) 50 Pack $334.80
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    R1109-E DNA/RNA Shield Collection Tube w/Swab (2 ml fill - CE) 50 Pack $360.50
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    Description & Documents Specifications FAQ Citations

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    Product Description


    Swab collection kits include DNA/RNA Shield Collection tubes with Swabs and are a general purpose collection method for molecular-based applications. Many sample types can be collected with these swab collection tubes including from the mouth, nose, throat, and wherever a swab may be deemed appropriate per application. To use these swab collection tubes, just swab any sample and break the tip into the collection device prefilled with the DNA/RNA Shield reagent. Samples are stabilized and ready for transport or storage.

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    Technical Specifications

    Applicable For Next-Generation Sequencing, qPCR, microarray
    Device Specs 12 x 80 mm screwcap vial pre-filled with DNA/RNA Shield (1 mL or 2 mL)
    Device Storage Ambient temperature => 2 years
    Sample Collection 10% (v/v or w/v)
    Sample Source Nose, mouth, throat, biological fluids, environmental samples

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    Transfer tissues in to DNA RNA Shield at room temperature, submerge. Tissue can be homogenized or stored frozen prior to homogenization.

    Yes, extracted nucleic acids are stabilized in DNA/RNA Shield. Prior to downstream applications, clean-up the sample via the appropriate Zymo Research clean-up kit (Genomic DNA Clean and Concentrator (gDCC), DNA Clean and Concentrator (DCC), and RNA Clean and Concentrator (RCC)).

    DNA/RNA Shield can be used on a wide variety of sample types including cells, tissues, biological fluids (plasma, serum, saliva, urine), and environmental samples (feces, plants, swabs, etc.).

    RNA > 1 month
    DNA > 2 years

    DNA & RNA (<-20°C): Indefinitely

    This can happen on occasion due to transport or storage at lower temperatures. The reagent functionality is not affected; however, the precipitate can be resolved by heating the reagent to >37 °C.

    No, tissues do not need to be homogenized.

    Yes, sort directly into DNA/RNA Shield (e.g. Collect 100 µl of FACS sorted cells into minimally 400 µl of DNA/RNA Shield).

    Avoid mixing the reagent and bleach (sodium hypochlorite) or other strong oxidizing agents and acids. Clean up any accidental spills with water first.

    For any biological sample collection (nasal, throat, etc.), use a sterile swab for collection and then deposit it into DNA/RNA Shield. For application-specific questions, please reach out to technical support.



    “I’m a Zymo fan! DNA/RNA Shield is a great product. It works great on my precious samples. I trust Zymo Research products and they have great tech support!!”

    - Laura T. (USDA)

    “We use DNA/RNA shield and it works well with adults mosquitoes, larvae, eggs. We store it at RT for weeks and at -4°C or -20°C for months, never saw any DNA degradation.”

    - Umberto P. (University of Pavia)

    “I did an assay using RNA/DNA shield and it works perfect. The product have excellent reproducibility when stored at 4°C for up to a month.”

    - Maha AE. (University of Florida)


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