All-Inclusive Genomic
Sequencing Solutions
Get Reliable, Accurate Results from
Your Most Challenging Samples
Compatible with
Any Sample
Get reliable NGS insights from low-input and challenging samples, including FFPE, liquid biopsy, soil, microbes, and more.
Accurate Results,
Every Time
Achieve unparalleled accuracy, depth, and precise variant detection from every sequencing run.
Fastest
Turnaround Time
Our expert NGS scientists are capable of a turnaround time as short as 5 days, the fastest in the industry.
Genome Sequencing Services
Your Trusted Partner for Genomics Discovery
Many of today's complex research projects require the in-depth, accurate insights that only next-generation sequencing (NGS) can provide. Save time and resources by partnering with Zymo Research for all your genomic sequencing needs. From sample preparation to sequencing and bioinformatics analysis, we provide an end-to-end solution.
Our comprehensive genomic sequencing services combine the strengths of PacBio HiFi long-read technology and Illumina short-read sequencing. This unique pairing provides unparalleled accuracy and depth for whole-genome sequencing, enabling a thorough understanding of complex genomes. Paired with our industry-leading products for sample collection and purification, this sequencing solution makes it possible to precisely analyze challenging sample types such as FFPE, cfDNA, complex genomes, and so on. Leverage our state-of-the-art technology and decades of expertise to take your genomics research to the next level.
A Customized Sequencing Solution for Any Sample
From Sample Preparation to Bioinformatics Analysis, We've Got You Covered
Sample
Collection
- Preserve nucleic acid at room temperature, without cold chain shipping.
- Inactivate pathogens for safe handling.
- Easy-to-use devices available for most sample types.
DNA
Extraction
- Recover ultra-pure, high-yield DNA from any sample.
- Simple, user-friendly purification protocols.
- Compatible with popular automation platforms for high-throughput sample processing.
Library
Preparation
- The simplest and fastest NGS library prep workflow available, complete in just 3 hours.
- True end ligation for reliable and precise genomic data from difficult sample types.
- Universal cost-effective workflow.
Next-Generation Sequencing
- Broad portfolio of services, including whole-genome, long-read, and targeted sequencing options.
- Accurate sequencing data from every run.
- Cutting-edge Illumina and PacBio sequencing technology.
Bioinformatics & Data Analysis
- Expert guidance on sequencing data analysis and interpretation.
- Comprehensive, easy-to-interpret analysis reports.
- Publication-ready data figures.
Genome Sequencing Offering
Supporting Your Genomics Analysis & Discovery
Whole-Genome Sequencing
Analyze the entire genome with comprehensive, high-resolution data, ideal for capturing known and novel mutations.
Long-Read Sequencing
Generate reads spanning large and complex genomic regions, ideal for de novo genome assembly or characterizing structural variants.
User-Friendly & Comprehensive Reports
From Bioinformatics to Publication-Ready Figures
Analysis Includes:
- Complete data quality assessments
- Variant identification and reporting
- Actionable disease-related reports
True-End Analysis in cfDNA
Our genomic sequencing service employs innovative Splinted Ligation Adapter Tagging (SPLAT) technology, enabling accurate and high-fidelity analysis of fragmentation patterns. The Zymo-Seq™ SPLAT DNA library preparation method reveals more DNA fragment information than standard dsDNA library preparation systems. The unique single-stranded SPLAT approach captures enriched short cfDNA fragments compared to the dsDNA library prep method, making it advantageous for sequencing a wide range of sample types.
High-Quality SNP and INDEL Performance
PrecisionFDA Truth Challenge
Genomic sequencing workflows featuring the Zymo-Seq™ SPLAT DNA Library Kit produce reliable SNP and INDEL calling according to the Precision FDA Truth Challenge guidelines. Zymo-Seq™ SPLAT DNA Libraries were prepared from both genomic (NA12878) and FFPE-derived (FF12878) HG001 genome reference DNA samples. Variant calling was performed using DeepVariant. The accuracy metrics for SNP and INDEL detection were evaluated following the Precision FDA Truth Challenge workflow, comparing the results to the ground truth reference data. Overall performance of the Zymo-Seq™ SPLAT libraries shows superior results across both genomic and FFPE-derived DNA input.
Trusted By Leading Institutions
We are proud to have provided high-quality, reliable next-generation sequencing services to some of the world's leading organizations across diverse industries such as health care, consumer goods, pharmaceuticals, food safety, skin care, agriculture, and academic research.
Technical Specifications
| Sequencing Platforms | Illumina, PacBio |
| Read Length | From paired-end 75 up to 300 cycles |
| Sequencing Depth | ~30X for whole-genome, or ≥1000X depth for targeted panels |
| Accepted Sample Types | DNA/RNA, tissue, culture, liquid biopsy, cell-free, FFPE, etc. |
| Library Prep | Zymo-Seq SPLAT DNA Library Kit (Cat. No. D5464), tagmentation, custom panels |
| Data Visualization | User-friendly customized HTML reports |
Questions? We're Here to Help.
In line with our 100% Customer Satisfaction Guarantee, our team of NGS experts is ready to provide tailored guidance and dedicated support for your genome sequencing project. Schedule a consultation today to learn how partnering with Zymo Research can elevate your genomics research while saving you time and expense.
Other Sequencing Services
Supporting Your NGS Analysis & Discovery
Microbiomics
Solutions for accurate microbiome profiling, including 16S/ITS amplicon sequencing, full-length 16S sequencing, shotgun metagenomic sequencing, long-read metagenomic sequencing, and metatranscriptomic sequencing.
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Transcriptomics
Total RNA sequencing solutions for comprehensive gene expression analysis and microRNA sequencing options for small RNA research.
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Epigenomics
Explore epigenetic modifications associated with aging and cancer, using targeted bisulfite sequencing, genome-wide DNA methylation sequencing, and ChIP sequencing to unveil changes in DNA methylation and chromatin structure.
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