A World of DNA Methylation

Join Zymo Research in advancing early detection and stratification of any cancer with our DNA methylation technologies!

  • Most-cited reagent & NGS library platforms for methylome mapping
  • CE-IVD certified bisulfite reagents for automation
  • The most accurate solution for clinical samples: cfDNA, FFPE

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Elevating Epigenetics, Simplifying Science

Zymo Research embarks on a new chapter of innovation in epigenetic technologies and platforms, continuing our legacy of impactful success to further advance global epigenetic research and applications.

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cfDNA Mastered: Methyl-seq Simplicity

Effortless 3-step process for methyl-seq libraries that feature low 5ng input, gentle bisulfite, and direct adapter ligation.

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Reveal the Epigenetic Landscape

ATAC-Seq unleashed: Streamlined 4-hr workflow from as little as 50K cells with gentle lysis, transposase magic, and UDI tagging.

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A World of DNA Methylation

Elevating Epigenetics, Simplifying Science

cfDNA Mastered: Methyl-seq Simplicity

Reveal the Epigenetic Landscape

The Epigenetics Company™

Boasting over twenty years of leadership in the field of epigenetics, we set the benchmark for excellence through industry-leading products, providing top-tier technology and services for cancer research, aging, neuroscience, and therapeutic exploration. Our dedication to innovation, coupled with personalized support from genuine scientists, offers researchers an unparalleled journey through the intricacies of epigenetics.

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Celebrating 30 Years of Passion and Innovation!

Mark Zymo Research's 30th anniversary in style with our special offer: receive a complimentary "You can thank my Epigenetics!" Limited Edition T-Shirt with any purchase of Epigenetics products.

Use Promo Code: EPMAY24

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Knowledge Center

What is Epigenetics?

“Epigenetics” refers to covalent modification of DNA, protein, or RNA, resulting in changes to the function and/or regulation of these molecules, without altering their primary sequences.

What is DNA Methylation?

DNA methylation is a chemical modification to DNA molecules. DNA methylation is among the most extensively studied epigenetic marks that regulate gene expressions. DNA methylation is essential in organismal development and homeostasis maintenance.

Bisulfite Beginner Guide

Bisulfite beginners guide contents include an overview of quantification of bisulfite-converted DNA assessing quality of bisulfite-converted DNA bisulfite PCR. Read our Bisulfite 101 guide today!

Bisulfite beginners guide contents include an overview of quantification of bisulfite-converted DNA assessing quality of bisulfite-converted DNA bisulfite PCR. Read our Bisulfite 101 guide today!

Controls for DNA Methylation

Elevate DNA methylation research with expert control strategies in our FREE Application Note, optimizing experiments and choosing the right controls for precision in epigenetic studies.

Elevate DNA methylation research with expert control strategies in our FREE Application Note, optimizing experiments and choosing the right controls for precision in epigenetic studies.

Scientific Advisory Board

Our elite Scientific Advisory Board includes Ph.D's, and Directors of Science from leading Academic Universities and Institutions around the globe.

Our elite Scientific Advisory Board includes Ph.D's, and Directors of Science from leading Academic Universities and Institutions around the globe.

The New Age of Forensic Science

After suspect Steven Avery is implicated in two separate crimes happening 2 decades apart, the validity of the samples was in question. Scientists used DNA methylation to try to solve the case.

After suspect Steven Avery is implicated in two separate crimes happening 2 decades apart, the validity of the samples was in question. Scientists used DNA methylation to try to solve the case.

Bisulfite Conversion for Illumina Methylation Arrays

Troubleshooting and best practice guidelines for bisulfite conversion for Illumina methylation arrays, including the Infinium™ Mouse Methylation BeadChip.

Troubleshooting and best practice guidelines for bisulfite conversion for Illumina methylation arrays, including the Infinium™ Mouse Methylation BeadChip.

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Tools

Image for the Bisulfite Primer Seeker Program

Bisulfite Primer Seeker

This program reflects Zymo Research’s simplification of the tedious process of bisulfite primer design. This program will help you design primers in particularly CG-rich sequences and will provide you with multiple options for amplicons that span different regions within your sequence.

Solutions for Epigenetics Research

DNA Methylation Library Prep

Methylome mapping for any sample

DNA Methylation Standards

 The premier benchmarks for all DNA methylation assays

Bisulfite Methods

CE-IVD certified, automation-ready and most trusted bisulfite reagents

Non-Bisulfite Methods

Ideal solutions for a rapid methylation screening

Chromatin Analysis

Streamlined solutions for profiling chromatin

Epigenetic Enzymes & Reagents

Popular epigenetic enzymes and reagents

Featured Technologies

New
Lightning

EZ-96 DNA Methylation-Lightning MagPrep

Explore a top bisulfite conversion kit

Discover the fastest bisulfite conversion kit with the most efficient method for complete bisulfite conversion of DNA for methylation analysis.

Trending
Standards

Human Methylated & Non-methylated DNA Set

Controls for accurate bisulfite conversion and quantification

Methylated and non-methylated DNA controls to assess bisulfite conversion efficiency and for DNA methylation quantification.

Most Cited
OneStep

OneStep qMethyl-PCR Kit

Rapid Methylation: Bisulfite-Free, Loci Screening

A bisulfite-free DNA methylation analysis; Rapid screening of single/multiple loci.

Trending
Zymo-Seq

Zymo-Seq ATAC Library Kit

Generate libraries in 4 hours from 50,000 cells

Prepare ATAC-Seq libraries from as few as 50,000 cells in as little as 4 hours from mammalian cells and tissue input.

NGS Services

Targeted Bisulfite Sequencing Service

MethylCheck™ platform simplifies epigenetic biomarker validation with targeted bisulfite sequencing service and expert support for DNA methylation changes.

Age Analysis Service

DNAge Epigenetic Age Analysis Service, using Dr. Horvath’s Clock, accurately quantifies biological age in human and mouse samples, offering insights into life factors' impact.

Genome-Wide DNA Methylation Analysis

Comprehensive & Reliable services for DNA methylation sequencing analysis

ChIP-Seq Analysis Service

Customizable ChIP-Seq analysis service delivers high-quality, publication-ready data for chromatin immunoprecipitation and next-gen sequencing.

Custom & OEM Solutions

Your Custom and OEM Solutions Partner

Zymo Research experts work closely with you to facilitate your custom manufacturing needs and bring your vision to life with ISO 9001 and ISO 13485 capabilities.

Talk to an Epigenetics Expert

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