How to Boost Reliability & Reproducibility with Controls for DNA Methylation Assays

DNA methylation is a powerful, well-studied epigenetic mark and has been rapidly adopted into clinical applications such as cancer diagnostics, aging and beyond. High quality controls are required for all scientific testing, including DNA methylation assays. This application note demonstrates the importance of DNA methylation controls from experiment design to day-to-day testing and includes suggestions on how to choose best controls for different assay type from PCR to NGS.

Application Note Highlights:

• How controls assist experiment optimization and workflow validation
• Practical guides for utilizing controls
• DNA methylation control recommendations